The efficacy of laparoscopic cholecystectomy versus that of conventiona] open cholecystectomy for acute cholecystitis

Abstract

Objective To investigate the efficacy of laparoscopic cholecystectomy ( LC ) for acute cholecystitis.Methods The clinical data on 186 patients undergoing LC and 287 patients undergoing open cholecystectomy ( OC ) were retrospectively analyzed and the patients were divided into LC group and OC group.Length of hospital stay,surgical duration,intraoperative bleeding volume,time to ambulation after surgery,time to anal exhaust,rate of placing drainage tube,drainage amount of abdominal cavity,rate of incisional infection,and changes in levels of CRP and PA were compared between the two groups.Results Length of hospital stay,surgical duration,and time to anal exhaust were significantly shorter and intraoperative bleeding volume was smaller in LC group than in OC group ( P＜ 0.05 ).There were no significant differences in the rate of placing drainage tube and in drainage amount of abdominal cavity between LC group and OC group ( P＞ 0.05 ).CRP level was obviously higher in OC group than in LC group ( P ＜ 0.01 ); whereas PA level significantly declined in both groups as compared with the baseline ( P ＜ 0.05 ), more markedly in OC group ( P ＜ 0.01 ).Conclusions Laparoscopic cholecystectomy for acute cholecystitis is less invasive and can evidently relieve pain in patients and save medical resources.It is a feasible,safe,effective surgical procedure. Key words: Acute cholecystitis; Laparoscopiec cholecystectomy; Open cholecystectomy