Abstract

1. 1. The presence of 2.5 mmoles/1 of stable Zn 2+ increases the uptake of 85Sr 2+ and 133Ba 2+ by bone powder and by anorganic bone from solutions that contain these radioisotopes in tracer quantities, whereas the presence of stable Ca 2+ or Ba 2+ decreases uptake. The presence of stable Ca 2+ or Ba 2+ does not appreciably affect the uptake of tracer quantities of 65Zn 2+. 2. 2. The results support the hypothesis that Zn 2+ distorts the surface of the crystals of bone mineral and thus facilities the replacement of Ca 2+ by larger alkaline earth ions. The effect is found when tracer amounts of the alkaline earth ions are used but not when the concentrations of these ions are of the order of 2.5 mmoles/l.

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