Abstract

Introduction. Consumption of unripe grape juice (verjuice) has been portrayed by the traditional belief, as a means of combating dyslipidemia. We aimed to evaluate the effects of unripe grape juice consumption on lipid profile in healthy human volunteers. Methods. We asked 42 enrolled volunteers to drink 10 cc of verjuice within 30 minutes to 2 hours after lunch and 10 cc of it after dinner. After taking 120 doses of verjuice, another fasting lipid profile was obtained from each participant. The statistical analysis was performed by SPSS 13 software. Results. After analysis of the data, the mean ± standard deviation for all the variables was obtained. Among those improvement of HDL-C was significant after the trial (P value < 0.001). TG, TC, and LDL improvement were not significant. Conclusion. Our study declared that verjuice has a dramatic effect on improving HDL-C level of serum but no any other lipid improvement effect was obtained.

Highlights

  • Consumption of unripe grape juice has been portrayed by the traditional belief, as a means of combating dyslipidemia

  • Is it reaping the fruitage of what it has sown for centuries? As we endeavor to this vital question, we found few studies conducted on verjuice, which have been done recently with extremely different conclusions

  • The study population consisted of 42 volunteers with impaired lipid profile, who enrolled between November 1, 2011, and February 12, 2012

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Summary

Introduction

Consumption of unripe grape juice (verjuice) has been portrayed by the traditional belief, as a means of combating dyslipidemia. After analysis of the data, the mean ± standard deviation for all the variables was obtained Among those improvement of HDL-C was significant after the trial (P value < 0.001). Unripe grape juice use (verjuice) in many ways is prevalent in Iranian families’ meals which include mixing with different kinds of salads, for changing the taste of foods to sour, and even drinking some amount of it. This extensive use may be the reason of the general belief in Iranian traditional medicine that verjuice has some lipidlowering effects [4]. Is it reaping the fruitage of what it has sown for centuries? As we endeavor to this vital question, we found few studies conducted on verjuice, which have been done recently with extremely different conclusions

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