The Effects of Sedation on Auditory Brainstem Response in Pediatric Population: A Systematic Review

Abstract

Background and Aim: Auditory Brainstem Response (ABR) is crucial for evaluating auditory pathway function in pediatric patients. However, obtaining reliable ABR measurements in young children can be challenging due to their inability to stay still and quiet during the test. Sedation is frequently used to facilitate ABR testing in this population, but the most practically effective sedation method and its impact are still uncertain. This systematic review aimed to thoroughly investigate the success rates (completion of ABR in both ears) associated with different sedation techniques. Recent Findings: In recent review (2000-2022), Ten studies, identified through a comprehensive search of electronic databases, were included in the analysis. The studies reported significant variation in success rates for ABR testing with sedation, ranging from 70% to 100%. This suggests that the effectiveness of sedation may not be uniform across all situations. The included studies employed a wide variety of sedation techniques, highlighting the lack of a standardized approach in this area. Conclusion: These findings highlight the heterogeneity in sedation practices and success rates for pediatric ABR testing. This emphasizes the importance of tailoring the sedation approach to the specific needs of each child while carefully considering the potential risks associated with each sedation method. Further research is warranted to establish standardized protocols for sedation in pediatric ABR , ensuring optimal test efficacy while prioritizing patient safety. Research Square registration.Keywords: Auditory brainstem response; sedation; chloral hydrate; children; dexmedetomidine; intranasal drug administration