Abstract
Aim-Background Improvements and developments in the treatment of early breast cancer include the use of breast-conserving therapy and radiotherapy in place of radical mastectomy, chemotherapy, monoclonal antibodies and hormone therapy. Radiation to the heart causes both acute and chronic symptoms of cardiac toxicity. Acute symptoms include acute pericarditis, pericardial effusion and arrhythmias. Among the long-term effects are constrictive pericarditis and increased atherosclerosis. The risk is greatest with left breast irradiation and radiation involving internal mammary lymph nodes. In this paper, we discuss the cardiovascular effects of radiation therapy treatment of early breast cancer.
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