Abstract

Biological Mechanisms and Models for New Approaches to Adjuvant Therapy of Breast Cancer.- Patterns of Treatment Failure - Implications for New Treatment Approaches.- New Information on Drug Resistance: Implications for the Adjuvant Treatment of Breast Cancer.- Correlation of Dose Intensity and Prognosis in Adjuvant Chemotherapy: An Extended Controversy.- Dose Response for Adjuvant Chemotherapy of Breast Cancer: Experimental and Clinical Considerations.- Neoadjuvant (Pre- and Perioperative) Therapy.- Experimental Basis and Clinical Reality of Preoperative (Neoadjuvant) Chemotherapy in Breast Cancer.- Neoadjuvant Chemotherapy in the Conservative Management of Breast Cancer: A Study of 252 Patients.- Randomized Perioperative Therapy in Operable Breast Cancer: The Ludwig Trial V.- Is There a Role for Perioperative Adjuvant Cytotoxic Therapy in the Treatment of Early Breast Cancer?.- Problems of Rational Follow-up and Salvage Therapy.- Radiation Therapy in Prevention and Salvage of Local Relapse: Its Prognostic Implication.- Salvage Treatments in Relapsing Resectable Breast Cancer.- Time Course and Prognosis of Mammary Failure Following Breast-Conserving Therapy.- Detection of Recurrence: A Critical Assessment of Existing Methods and Programs.- Factors Associated with Local Recurrence as a First Site of Failure Following the Conservative Treatment of Early Breast Cancer.- Critical Review of Problems of Rational Follow-up and Salvage Therapy.- Adjuvant Therapy in Premenopausal Patients.- Endocrine Effects of Adjuvant Chemotherapy in Premenopausal Women: Suggestions for the Future.- The Milan Experience with Adjuvant Chemotherapy in Premenopausal Breast Cancer.- Adjuvant Chemo- and Endocrine Therapy Alone or in Combination in Premenopausal Patients (GABG Trial 1).- Scottish Adjuvant Breast Cancer Trials: Results in Pre-menopausal Patients.- Critical Review of Adjuvant Therapy in Premenopausal Patients.- Adjuvant Therapy in Postmenopausal Patients.- The Role of Adjuvant Endocrine Therapy in Primary Breast Cancer.- How to Improve Adjuvant Treatment Results in Postmenopausal Patients.- Adjuvant Chemo-Endocrine Therapy or Endocrine Therapy Alone for Postmenopausal Patients: Ludwig Studies III and IV.- Chemo- or Endocrine Adjuvant Therapy Alone or Combined in Postmenopausal Patients (GABG Trial 1).- Prognostic Factors and Treatment for Node-Negative Patients.- Prognosis in Breast Cancer.- Adjuvant Chemotherapy for Node-Negative Breast Cancer Patients.- Significant Survival Benefit of Node-Negative Breast Cancer Patients Treated with Adjuvant Chemotherapy: Seven-year Results.- Adjuvant Immunotherapy in Node-Negative Patients: Results of a Scandinavian Study.- Breast-Conserving Surgery and Adjuvant Radiotherapy.- Breast-Conserving Surgery and the Role of Adjuvant Radiotherapy: A Review.- New Trends in Breast Cancer Surgery.- Therapy of Early Breast Cancer: Preliminary Results of the German Breast Cancer Study.- Methodology of Adjuvant Trials and Interpretation of Results.- Methods for Assessing Treatment Efficacy in Trials for Adjuvant Therapy for Breast Cancer.- Overview of Adjuvant Radiotherapy for Breast Cancer.- Randomized Multicenter 2 x 2-Factorial Design Study of Chemo/Endocrine Therapy in Operable, Node-Positive Breast Cancer (Protocol 2).- Critical Review: Methodology of Adjuvant Trials and Interpretation of Results.- Quality of Life: Psychological Aspects of Adjuvant Therapy of Breast Cancer.- Adjuvant Therapies in Breast Cancer and Quality of Life: A Critical Review of the TWiST Concept.- Rehabilitation of Patients with Primary Breast Cancer: Assessing the Impact of Adjuvant Therapy.- Coping and Survival in Patients with Primary Breast Cancer: A Critical Analysis of Current Research Strategies and Proposal of a New Approach Integrating Biomedical, Psychological, and Social Variables.- Behavioral Side Effects of Adjuvant Chemotherapy.- Critical Review of Quality of Life: Psychosocial Aspects of Adjuvant Therapy in Breast Cancer.- Closing Summary and Outlook.

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