The effects of ocular contusion on corneal endothelium

Abstract

Objective To investigate the influence of ocular contusion on corneal endothelium.Methods Twenty-seven eyes of 27 cases of ocular contusion were enrolled in the study as the clinical trial group.The contralateral healthy eyes of all cases were regarded as the control group.The corneas was measured by non-contact specular microscope.The data were analyzed by SPSS 16.0.A P value less than 0.05 was considered statistically significant.Results The corneal endothelial cell density (CD) in the experimental group (1840.80 ± 332.87)/mm2 was lower than the control group (2694.30 ± 211.32)/mm2 significantly (t =9.729,P ＜0.01).The average cell area (ACA) in the experimental group (568.16 ± 147.61) μm2 was larger than the control group (359.33 ± 69.07) μm2 significantly (t =6.463,P ＜ 0.01).The standard deviation of average area in the trial group (243.41 ± 135.45) was bigger than the control group (161.12 ± 19.00) significantly (t =4.765,P ＜ 0.01).The coefficent of variation of cell size in the trial group (41.10 ± 10.17) ％ was larger than the control group (31.01 ± 3.53) ％ significantly (t =4.915,P ＜ 0.01).The percentage of hexagonal cells (6A) of the trial group (49.88 ± 9.07) ％ was smaller than the control group (57.71 ± 5.30) ％ significantly (t =3.581,P ＜ 0.01).Conclusion Compared with the healthy eyes,corneas with ocular contusion has smaller CD and 6A,larger ACA,CV and standard deviation. Key words: Contusion, ocular; Endothelium, corneal