Abstract
This retrospective cohort study aimed to examine the rehabilitation effect of patients with coronavirus disease 2019 (COVID-19) in the intensive care unit (ICU) under mechanical ventilation and included ICU patients from a university hospital who received rehabilitation under ventilator control until 31 May 2021. Seven patients were included, and three of them died; thus, the results of the four survivors were examined. The rehabilitation program comprised the extremity range-of-motion training and sitting on the bed’s edge. The Sequential Organ Failure Assessment score (median (25–75th percentiles)) at admission was 7.5 (5.75–8.5), and the activities of daily living (ADLs) were bedridden, the lowest in the Functional Independence Measure (FIM) and Barthel Index (BI) surveys. Data on the mean time to extubation, ICU length of stay, and ADLs improvement (FIM and BI) during ICU admission were obtained. Inferential analyses were not performed considering the small sample size. The mean time to extubation was 4.9 ± 1.1 days, and the ICU length of stay was 11.8 ± 5.0 days. ΔFIM was 36.5 (28.0–40.5), and the ΔBI was 22.5 (3.75–40.0). Moreover, no serious adverse events occurred in the patients during rehabilitation. Early mobilization of patients with COVID-19 may be useful in ADLs improvement during ICU stay.
Highlights
There are over 190 million cases of coronavirus disease (COVID-19) infections worldwide, with the number of deaths exceeding 4 million on 20 July 2021 [1].Approximately 80% of patients have mild diseases, not requiring hospitalization, while the remaining 20% require treatment, with 5% being admitted to the intensive care unit (ICU)and requiring ventilator management [2,3]
This study aimed to provide information for suggesting early reWe hypothesized thatpatients early rehabilitation provision is effective even aimed in severely ill habilitation programs for with COVID-19
The results of this study suggest that early rehabilitation is effective for patients with COVID-19, without imposing a higher risk
Summary
There are over 190 million cases of coronavirus disease (COVID-19) infections worldwide, with the number of deaths exceeding 4 million on 20 July 2021 [1].Approximately 80% of patients have mild diseases, not requiring hospitalization, while the remaining 20% require treatment, with 5% being admitted to the intensive care unit (ICU)and requiring ventilator management [2,3]. There are over 190 million cases of coronavirus disease (COVID-19) infections worldwide, with the number of deaths exceeding 4 million on 20 July 2021 [1]. 80% of patients have mild diseases, not requiring hospitalization, while the remaining 20% require treatment, with 5% being admitted to the intensive care unit (ICU). Requiring ventilator management [2,3]. Patients often use extracorporeal membrane oxygenation (ECMO). Patients with severe COVID-19 pneumonia often receive prolonged ventilator management under deep sedation for lung protection. ICU-acquired weakness (ICU-AW) and disuse syndrome are likely to occur, resulting in lower activities of daily living (ADL) and longer hospital stays [4,5]. In mid-April 2021, securing hospital rooms for patients with severe COVID-19 became challenging in some Japanese regions, resulting in medical collapse [6]
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