Abstract

The effects of physiological doses of caerulein, a pure cholecystokinin analog, was measured on food intake of cats. Food intake was increased by caerulein when infused at 400 ng/kg/hr. However, at the lowest dose, a slight decrease of intake was observed suggesting that low levels of caerulein may inhibit food intake in this species. Slow infusion of caerulein as compared to bolus injection may have opposite effects on food intake, that is, stimulation with infusion and inhibition with injection.

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