Abstract
Candida albicans(C. albicans) is one of the bacteria that resides in the oral cavity, and the ones living in medical and commercial denture resins, commonly cause diseases. Therefore, this study was conducted to confirm the antibacterial activity of C. albicans using a denture base resin containing peony extract with antibacterial properties.
 For the antibacterial effect, optical density and confocal laser microscopy were used. Contact angle measurements and color change measurements were performed to confirm the physical change of the material added with the antibacterial agent to the denture reline resin.
 As a result of the antibacterial test, the experimental group exhibited antibacterial activity against C. albicans. Compared to the optical density results, the results of the experimental group showed a significant difference. As a result of Fluorescent images showing (confocal laser microscope), the control group showed a lot of live bacteria, no bacteria appeared in the experimental group. All group did not show any physical changes. As a result of the contact angle measurement, the surface of the experimental group was changed to hydrophilic. In addition, there was no change in the color of the denture reline resin containing peony extract. In conclusion, it was confirmed that the peony extract contained antibacterial activity of the denture resin, and further studies should be conducted on various bacteria for denture base resin disinfection.
Highlights
Several bacteria, which cause many diseases in the oral cavity, are present in denture basin resins (Kim D V et al, 2107)
As peony extract has previously been used as an inhibitor against Streptococcus mutans and C. albicans (Krzyściak W et al, 2017; Zhang Y et al, 2017], we placed it in the denture resin to study the possibilities of denture-induced stomatitis, In addition, previous researchers investigated the antibacterial effectiveness of peony extract for studying its use as an inhibitor (Bansal V et al, 2020)
Dendritic stomatitis can be related to Candia species, pharyngeal infection caused by Staphylococcus aureus, and upper respiratory tract infection (Shen C et al, 1989) It is essential to prevent bacterial colonies through proper hygiene management of tissue control materials; mechanical, and chemical cleaning can change the physical properties of materials
Summary
Several bacteria, which cause many diseases in the oral cavity, are present in denture basin resins (Kim D V et al, 2107). This study aims to produce a denture base resin containing a peony extract that is known to have antibacterial activity. As peony extract has previously been used as an inhibitor against Streptococcus mutans and C. albicans (Krzyściak W et al, 2017; Zhang Y et al, 2017], we placed it in the denture resin to study the possibilities of denture-induced stomatitis, In addition, previous researchers investigated the antibacterial effectiveness of peony extract for studying its use as an inhibitor (Bansal V et al, 2020). Due to the nature of the patient suffering from denture problems, the soft tissue inside the gingiva tends to be damaged (Stipho H D et al, 2001, Gundogdu M et al, 2015) we studied the effect of disinfectants on the stability of denture base acrylic resins, and found that they affected their color stability (May KB et al, 1992). In this study, the peony extract was prepared by including the denture tissue regulator, and the antibacterial activity, color change and contact angle were analyzed
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