THE EFFECTIVENESS OF THERAPEUTIC AND PREVENTIVE MEASURES TO SUPPORT HOMEOSTASIS OF THE ORAL CAVITY BEFORE URANOPLASTY IN CHILDREN WITH CLEFT PALATE

Abstract

The scientific publications are constantly active in improving the complexes of therapeutic and preventive measures in children with congenital indivisible palate, which are aimed at improving the quality of their life at all stages of observation. This issue is of particular relevance when it comes to surgery, which requires a well-balanced evaluation of somatic and local status in order to create favorable conditions for healing of the wound after radical uranostaphyloplasty.
 The purpose of work: The optimization of correction of homeostasis of oral cavity in children with indivisible palate before surgery.
 It has been continued monitoring of 21 patients aged 4 to 6 years with congenital indivisibility of the palate, which in the presence of anatomical violations was divided into two groups with a one -sided vaccination of 12 people and bilateral 11.
 A comprehensive analysis of the primary results of the examination allowed them to determine in them decreasing the production of oral fluid and the violation of its qualitative properties, which led to changes in physicochemical, biochemical parameters. This prompted us to develop and test a complex of treatment and preventive measures during the preoperative period during the month. Its use in children with unilateral clefts allowed to partially normalizing the rate of salivation, the concentration of hydrogen ions in the oral fluid, its optical density, viscosity. In this case, the activity of α amylase was reduced by 1.3 times, and the number of medium mass molecules, the level of sialic acids, the content of total protein, oxyproline remained less in 1.2; 1.3; 1.3; 1.2 times, respectively, compared to the previous examination. The magnesium rate increased slightly, the phosphorus content of it increased by 1.3 times, the calcium-phosphorus coefficient and the mineralizing potential of the oral fluid were by 1.3 and 1.2 times, respectively, but they did not reach the control values.
 At the same time, children with bilateral non -growing palate during this period of examination have been able to achieve relative normalization of only the rate of salivation, pH, and mouth viscosity. There was an improvement in its optical density, the level of medium mass molecules, sialic acids and the total protein content by 1.3 times. The activity of α-amylase fell by 1.2 times, and the amount of oxyproline decreased by 1.4 times.
 The content of magnesium and calcium in it increased by 1.4 times, as well as the calcium-phosphorus coefficient. This traced the fall in phosphorus by 1.2 times, which was accompanied by an increase in the degree of mineralization of the potential of the mouth fluid by 1.5 times. In this way, we have achieved the goal.