Abstract

The presence of congenital non-union of the palate in children does not allow to carry out hygienic measures to the full extent, therefore it requires carrying out planned remedial and medical and preventive measures at all stages of observation. The purpose of the work is to study the long-term outcomes of the effectiveness of treatment and preventive measures after the radical uranostaphyloplasty. Research methods. In order to objectively assess the dental situation in 17 patients, we assessed the hygiene indices of Green-Vermillion, Silness-Loe, РМА SBI, saliva secretion rate, oral fluid pH, optical density, viscosity, α-amylase activity, medium molecular weight content, the presence of sialic acids, and the content of total protein and oxyproline. Results and discussion. When examining children in 6 months after surgery, it was found out that during this period of time the Green-Vermillion, Silness-Loe and bleeding indexes worsened by 1,3; 1,2; 1,3 times, respectively, and the PMA index increased by 1,4 times. The picture of changes in the physicochemical and biochemical components of oral fluid and its qualitative properties looks different. We would like to remind you that after the completion of the first course of treatment and prevention measures, we failed to normalize the levels of some of them. Over a period of time of 6 months, there was a deepening of the negative trend and the rate of salivation was by 1,3 times lower, but the activity of α-amylase improved by 1,2 times compared to the previous period of examination. The indexes of average mass molecules, sialic acids, total protein and oxyproline increased again by 1.5; 1,4; 1,2; 1,3 times, respectively. The fact of the stability of indexes of hydrogen ion concentration, optical density and viscosity was encouraging, which indicated an improvement in the rheological properties of oral fluid. This situation prompts the need to develop new methodological approaches regarding long-term observation of children with congenital non-union of the palate and determining an algorithm for their medical support. Conclusion. Persistent deterioration in hygiene indexes, periodontal tissue condition, salivary gland secretory activity, and qualitative properties of oral fluid cannot be fully resolved even in the long term after surgical intervention. This necessitates regular treatment and preventive measures, along with continuous improvement of these strategies. Prospects for further research. Further research is planned.

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