Abstract
This study is aimed to find out the effectiveness of oral 600 mcg single dose misoprostol for the evacuation of conception remnant in cases of incomplete abortion. This research is done by quasi experimental method with one group pretest – posttest design. The population of the study is all women who were diagnosed with incomplete abortion in less than 12 weeks of gestation in Cipto Mangunkusumo National general Hospital and affiliations hospital from June 2018 to June 2019. Women who met the study criteria, was treated with oral misoprostol 600 mcg single dose and then undergo conception evacuation evaluation and side effects evaluation. Effectiveness evaluation was seen after 7 days of single dose 600 mcg of misoprostol by measuring <15 mm endometrial thickness on transvaginal ultrasound. The effectiveness of using single dose oral misoprostol 600 mcg in the study participants was 93.55%, which were 29 out of a total of 31 participants. The side effects experienced after being given misoprostol were bleeding with less than the same amount as menstruation (71.0% and 9.0%), diarrhea (6.5%), and shivering (67.7%), and not found side effects of vomiting. Based on data analysis using paired T test before and 24 hours after administration of misoprostol, there was a significant difference between endometrial thickness (p value <0.001). Misoprostol 600 mcg per oral dose is effective for the evacuation of retained conception tissue of incomplete abortion at less than 12 weeks gestation, so that it can be an alternative non-operative method of evacuating retained conception tissue in incomplete abortion cases other than the operative method. Side effects found were bleeding, diarrhea, and chills. Side effects of vomiting were not found in this study.
Highlights
Abortion is a situation where conception tissues are expelled out of the womb before it is viable, which is less than 500 grams or less than 20 weeks of gestational age (Cunningham et al, 2014)
Spontaneous abortion is found in lower education levels, which are consistent with the findings by Zheng and colleagues in 2017
This study finds that the frequency of spontaneous abortions are lower in working females, which is consistent with this research’s findings, which collected data from 84,531 women in China (Zheng et al, 2017)
Summary
Abortion is a situation where conception tissues are expelled out of the womb before it is viable, which is less than 500 grams or less than 20 weeks of gestational age (Cunningham et al, 2014). The classification of abortion is the basis of its treatment, where in incomplete abortion, its treatment consists of stabilizing hemodynamic status and evacuation of retained conception tissue. This evacuation can be done by expectative management, pharmacologic, of non-pharmacologic. Several researchers, Paritakul and Phupong (2010), Diop and colleagues (2009), Nguyen and colleagues (2004), Weeks and colleagues (2005), and Shwakerela and colleagues (2007), Dao and colleagues (2007), and Bique and colleagues (2007) reports that using oral 600 mcg misoprostol for the evacuation of retained conception tissue of incomplete abortion is relatively an effective method
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