Abstract
1. 1. The effects of the addition of zinc and magnesium ions to cyanide-inhibited ox kidney phosphatase preparations have been studied. 2. 2. Zinc ions in low concentrations had a reactivating effect on the cyanide-inhibited enzyme, whereas magnesium ions had little effect. The effect of a mixture of these ions was dependent on their absolute amounts. 3. 3. Although there were evidences of slight tendencies for a shift of optimum pH on the addition of the metallic ions to the cyanide-inhibited enzyme, the changes were too small to support the general hypothesis of Sadasivan that the pH optima can be shifted by varying the ratios of zinc and magnesium ions. 4. 4. Comparison of the effects observed with ox kidney preparations and a human kidney phosphatase preparation was made.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call