The Effect Of Silver-Coated Endotracheal Tube On The Incidence Of Ventilator-Induced Pneumonia In Intubated Patients Admitted To The Intensive Care Unit (ICU)

Abstract

Background and Aim: Ventilator-associated pneumonia (VAP) is one of the main problems of intubated patients in the intensive care unit. the antibacterial endotracheal tube ara capable of reducing VAP via stopping bacterial colonization and biofilm formation. Therefore, in this study, the effects of silver-coated endotracheal tube on the incidence of VAP were investigated. Materials and Methods: In a single-blind clinical trial study, 108 patients in need of intubation were selected and divided into two intervention groups (antibacterial endotracheal tube) and control (standard non-coated endotracheal tube). Demographic information, secretion volume and shape, leukocytosis, decreased oxygen saturation, fever were recorded for all patients and compared in the two intervention groups. Results: The mean age (±SEM) in the intervention and control groups was 42.93 (±1.42) and 47.86 (±2.08) years, respectively. Furthermore, the incidence of VAP in the intervention and control groups was 5 (±1.8) and 8.5 (±2.1) days, respectively. Patients receiving a antibacterial endotracheal tube had a significantly reduction in the volume of secretions (P = 0.0027), incidence of purulent secretions (P = 0.04), fever (P = 0.019), leukocytosis (P = 0.0006), culture positive (P = 0.0001), and the onset of VAP symptoms (P = 0.001). The incidence of VAP in the intervention and control groups was 18% and 26%, respectively, and the antibacterial endotracheal tube significantly reduced the incidence of VAP (P = 0.0003). Conclusion: Silver-coated endotracheal tube?? has a more effective role in improving the prognosis of intubated patients admitted to the ICU when comparing with standard non-coated endotracheal tube.