Abstract
The purpose of this study was to determine whether or not the day of peak activity for rats showing regular estrous activity cycles is delayed by one day when sodium pentobarbital (Nembutal) is administered under the conditions found by Everett and Sawyer to be effective for delaying ovulation. Thirteen rats with regular 4-day estrous activity cycles received Nembutal and saline treatments on days of proestrus. Treatments were administered in a counterbalanced order; and after each, the day of peak activity in subsequent cycles was determined. For 12 of 13 animals treated with Nembutal the day of peak activity was delayed by one day; whereas for 11 of 12 animals, when saline was administered, the day of peak activity was not delayed.
Published Version
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