Abstract
Recently, there was a report that the 15-deoxy-Δ12,14-prostaglandin J₂ (15d-PGJ₂) reduced bony destruction in the mice with metastatic breast cancer and recovered the serum levels of bone turnover markers in the ovariectomized mice. They suggested that the 15d-PGJ2have not only ability of reducing destruction of bone, but also potential of regeneration of bone. On the basis of it, the purpose of this study is to evaluate the effect of 15d-PGJ₂ on regeneration of bone.
Published Version
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