The effect of intra-abdominal carbon dioxide pressure on blood pressure in laparoscopic surgeries

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Backgrounds: The high intra-abdominal carbon dioxide (CO2) gas pressure of the pneumoperitoneum may result in physiological changes. Objectives: This study aimed to examine the impact of high CO2 pressure on intraoperative blood pressures (BPs) in patients undergoing laparoscopy surgeries. Materials and Methods: In this quasi-experimental clinical trial, 36 patients diagnosed with different intra-abdominal diseases were undergone laparoscopic surgeries under a standard of CO2 pressure (≥13 mmHg). In another group, 39 patients who were matched in age and gender were undergone laparoscopic surgeries under low CO2 pressure (≤12 mmHg). Results: The patients in both high and low CO2 pressure groups were comparable in age (37.65 vs. 42.37 years; P = 0.114), gender (P = 0.212), and operation time (36.18 vs. 34.64 min), respectively. The patients underwent high CO2 pressure had significantly lower levels of diastolic BP after anesthesia (72.28 vs. 77.89; P = 0.020), lowest systolic BP (SBP) (94.69 vs. 102.26; P = 0.006), and lowest diastolic BP (DBP) (59.00 vs. 68.36; P