Abstract

Under conditions of free choice between water and diazepam solutions, Albino rats were reluctant to drink diazepam solutions in all but the lowest concentrations. Prolonged exposure to diazepam solutions did not result in increased intake. Electrical stimulation of the lateral hypothalamus which was previously shown to induce a permanent preference for ethanol in rats, and a schedule of “periodic withdrawal” shown to increase intake of ethanol in rats both failed to induce a similar preference or increased intake of diazepam solutions. The significance of these findings are discussed in terms of the postulated generality of the effect of both hypothalamic stimulation and periodic withdrawal.

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