Abstract

SummaryThe effect of hydrocortisone on the mastocytosis produced in the skin of mice by short-wavelength ultra-violet radiation was investigated. Two groups of mice were irradiated. The mice in one of the two groups also received hydrocortisone. It was observed that hydrocortisone distinctly reduced the tissue swelling produced by UV-radiation. In the group receiving radiation + hydrocortisone the mast cell counts distinctly decreased to below the control level. On the other hand in the group having mere radiation the mast cell counts clearly increased.

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