The effect of hyaluronic acid on conception rate of ectopic patients who underwent laparoscopic surgery treatment

Abstract

Objective To observe the clinical effect of hyaluronic acid on conception rate of ectopic pregnancy patients who received conservative tubal operation under laparoscopy. Methods 100 patients with ectopic pregnancy received conservative tubal operation under laparoscopy treatment were selected.Hyaluronic acid was used in 50 cases(the treatment group),unused anti blocking preparations for the control group in 50 cases. Then patients were followed up on the tubal patency,and observed pregnancy after 1 year. Results The rate of tubal patency after menstrual clean was 84% in the treatment group,which was significantly higher than 60% in the control group(χ2= 7.155,P< 0.05).In the treatment group,40 cases were intrauterine pregnancy,4 cases were ectopic pregnancy,6 cases were infertility.The rate of intrauterine pregnancy after 1 year was 80% in the treatment group,which was significantly higher than 56% in the control group(χ2= 6.65,P< 0.05). Conclusion Hyaluronic acid is effective in preventing tubal adhesion in the ectopic pregnancy patients who received laparoscopic conservative surgery,and can improve the postoperative tubal patency rate and conception rate. Key words: Sodium hyaluronate; Ectopic pregnancy; Laparoscope; Pregnancy rate