Abstract
Changes in the concentration of acid and alkaline phosphatases accompanying growth, in tissues other than bone, have been studied in chick embryos, healing wounds, and tumors (Moog, 1946). It therefore appeared of interest to determine whether or not arresting growth by hypophysectomy or stimulating it by injecting growth hormone alters the concentration of these enzymes in the liver and kidney of rats. Such experiments seemed the more pertinent because the growth hormone characteristically produces storage of nitrogen as protein (Lee and Schaffer, 1934; Young, 1945), and arguments for the implication of phosphatase in protein synthesis have been advanced (Moog, 1946). An increase in hepatic alkaline phosphatase in rats treated with adrenal cortex extracts (Kochakian and Bartlett, 1948) and changes in renal alkaline phosphatase during treatment with steroid hormones (Kochakian and Vail, 1944) also indicate the possibility of such a relationship. expeeimental The diets, feeding techniques, and animals were...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
