Abstract
BackgroundIn this trial, we investigated the effect of a group-based education program on gastrointestinal (GI) symptoms and quality of life (QOL) in patients with celiac disease (CD).MethodIn the present study, 130 patients with CD who were on a GFD for at least 3 months, randomly assigned to receive group-based education (n = 66) or routine education in the celiac clinic (n = 64) for 3 months. We assessed gastrointestinal symptoms and quality of life using the gastrointestinal symptom rating scale (GSRS) questionnaire and SF-36 questionnaire at baseline and 3 months after interventions.ResultsThe mean age of the participants was 37.57 ± 9.59 years. There were no significant differences between the two groups regarding the baseline values. Results showed that the mean score of total GSRS score in the intervention group was significantly lower compared with the control group 3 months post-intervention (p = 0.04). Also, there was a significant difference in the mean score of SF-36 between the two groups 3 months post-intervention (p = 0.02).ConclusionResults showed that group-based education was an effective intervention in patients with celiac disease to improve gastrointestinal symptoms and quality of life.Trial registration IRCT code: IRCT20080904001197N21; registration date: 5/23/2019.
Highlights
In this trial, we investigated the effect of a group-based education program on gastrointestinal (GI) symptoms and quality of life (QOL) in patients with celiac disease (CD)
Considering that only a limited number of studies had investigated the influence of group-based education on celiac patients, we designed a randomized controlled clinical trial (RCT) to compare the effect of group-based education and individualized education programs in patients with CD. we reported the result of the programs on knowledge and adherence levels in our previous report [26]
We provided the result of the effect of the group-based education program on gastrointestinal symptoms and quality of life in patients with CD
Summary
We investigated the effect of a group-based education program on gastrointestinal (GI) symptoms and quality of life (QOL) in patients with celiac disease (CD). Celiac disease (CD) is a chronic inflammatory condition of the small intestine that is triggered by the ingestion of gluten [1]. CD is associated with different gastrointestinal and extra-gastrointestinal symptoms including dermatitis, Complete elimination of gluten from the diet is the only available treatment [6, 7]. Non- adherence to a glutenfree diet (GFD) leads to a reduction in quality of life and worsening of symptoms [8,9,10]. A recent study in Iran indicated that 51.2% of Iranian patients with CD had higher than normal levels of serum anti-tTG-IgA [15]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
