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Abstract
The concentrations of creatine phosphate, ATP, ADP, AMP, lactate, pyruvate, hexose monophosphate, and glycogen were examined in skeletal muscle obtained from decapitated rats, or animals anesthetized with ether or pentobarbital.The concentrations of ATP, creatine phosphate, and glycogen were highest in muscles from pentobarbital-treated rats, whereas those of AMP, ADP, lactate, and pyruvate were the lowest in these animals. The data suggest that changes in the concentration of metabolites in skeletal muscle were less when the tissue was isolated under pentobarbital anesthesia than when it was isolated from decapitated or ether-anesthetized rats.
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