Abstract

Zinc oxide and eugenol (ZOE) and ZOE with 6% paraformaldehyde were implanted in vivo in the mandibles of dogs. ZOE produced a zone of changes in the bone which appeared to increase in size through the four-week term of the study. ZOE with paraformaldehyde produced a zone which was generally smaller than that of the ZOE specimens, with possible fixation of the tissue. The greatest extent of bone damage with the paraformaldehyde cement appeared to occur within the first week.

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