Abstract
The effect of diphenylhydantoin (Dilantin) on the myocardial uptake of 201Tl-chloride was studied in rats. Prior administration of Dilantin caused a significant (38.8) decrease in 201Tl uptake compared with the control group. No significant change in heart to blood or heart to muscle ratios was observed. Administration of Dilantin after 201Tl-chloride did not affect the myocardial concentration of the radionuclide.
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