Abstract

Creatine phosphokinase (CPK) is a binary enzyme that stimulates reverse phosphorylation to regenerate adenosine triphosphate. Creatine supplementation improves the Phosphagen system by increasing the amount of free creatine and phosphocreatine available to replenish adenosine triphosphate. The aims of this study are to investigate the effects of a creatine supplement on CPK enzyme, muscular endurance, power and agility performance compared to a placebo among wrestlers during the competition in a double-blind and randomized manner. Sixteen Wrestlers participated in the current study. They were divided into two groups; Experimental group (EXP) (n = 8) with creatine supplementation and a control group without creatine supplementation (CON) (n = 8). They were tested before (PRE) and after (POST) 8-week creatine supplementation period for CPK enzyme, muscular endurance [i.e. back-throw skill using the wrestling dummy], power [i.e. skill of the bridge], and agility [i.e. skill of the bridge in 10 sec.]. The results have shown statistically significant effects of the time (i.e. pre- to post-training) for all measured variables (p ≤ 0.05) of EXP group (whereas no significant effects (p ˃ 0.05) of CON group. There were statistically significant differences (p ≤ 0.05) at the POST evaluation of EXP group in comparison with CON group for all study variables.

Highlights

  • Performance-enhancing aids for athletes are classified into different categories such as mechanical aids, drugs, physiological aids, and nutrients. (Sabry, 2006(The intake of some supplements according to the athlete's need is a codified process that has positive effect on athletic reconstruction and strength recovery. (Shehata, 2000)Creatine has become one of the most common ingredients in dietary supplements, especially sports nutrition products. (Salama, 1999) It is an organic nitrogen compound, which is often obtained from external sources such as meat, fish and other animal products

  • Independent t-test was used to test for significant differences between experimental group (EXP) and creatine supplementation (CON) groups, a paired sample t-test was used to test for significant differences between PRE, and POST variables for each group

  • The control group Creatine phosphokinase (CPK) was (0.69%) and the experimental group was (171.43%). The researchers attribute this to the effect of creatine supply, which makes metabolic processes run normally unchanged, disrupting the desired and proper metabolic pathways. It shows that creatine supply ratios at those regulated doses gives a good indication of the safety of the successful application of the experiment which is consistent that most athletes before the competition try to increase creatine phosphate by loading this compound in standard doses It is similar to the results of the (Rafiq, 2016)

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Summary

Introduction

Performance-enhancing aids for athletes are classified into different categories such as mechanical aids (e.g. the use of lighter sports equipment, bicycle equipment designed to reduce air resistance), drugs (e.g. caffeine intake, male hormones, erythropoietin), physiological aids (e.g. sodium bicarbonate, sodium citrate, blood transfusion), and nutrients (e.g. carbohydrate supply, vitamins, amino acid subchains, creatine). (Sabry, 2006(The intake of some supplements (creatine, phosphorus, and amino acids, for example) according to the athlete's need is a codified process that has positive effect on athletic reconstruction and strength recovery. (Shehata, 2000)Creatine has become one of the most common ingredients in dietary supplements, especially sports nutrition products. (Salama, 1999) It is an organic nitrogen compound, which is often obtained from external sources such as meat, fish and other animal products. Creatine is found in a large amount in meat and fish, where each kilogram contains 5 grams of creatine. It can be replaced by internal sources, which are mainly synthesized in the liver, pancreas and kidneys from some of the essential amino acids, glycine, Arginine and Methionine (Abdel Fattah, 2003). The process of creatine formation takes place in three steps in the kidneys, liver and pancreas as follows: (1) In the first step, the amidine group moves amidin from arginine to the amino acid to form the compound of guanido. (2) In the second step, the group of Methionine moves from the amino acid to glyco ciamide to form creatine. The process of creatine formation takes place in three steps in the kidneys, liver and pancreas as follows: (1) In the first step, the amidine group moves amidin from arginine to the amino acid to form the compound of guanido. (2) In the second step, the group of Methionine moves from the amino acid to glyco ciamide to form creatine. (3) The third step removes a water molecule of creatine to form creatinine, which is excreted in the urine

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