Abstract
Summary The case history of a young female with severe idiopathic steatorrhea is described. Metabolic balances for fat, nitrogen and calcium, and intestinal absorption tests were studied before and during emergency ACTH and cortisone therapy. Dramatic clinical response was paralleled by a rapid fall in daily stool weight and prompt improvement in fat, nitrogen, and calcium absorption. Calcium balance data suggest that very large doses of oral vitamin D may be ineffective in relapses of sprue and that cortisone may promote calcium absorption independently of the action of vitamin D.
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