Abstract

Summary. The effect of chronic cold stress for periods of 0, 3, 5, 10, 20 and 30 days on metabolic activity in vitro, testis weight, total lipid, total carbohydrate, total carbohydrate on lipid free residue, ribonucleic acid (rna), deoxyribonucleic acid (dna) and percentage of lipid free dry weight of the testis was determined. Metabolic activities measured were endogenous oxygen consumption and oxygen uptake in the presence of exogenous glucose, succinate and a Krebs' cycle reaction system. Carbon dioxide, lactic acid production and glucose uptake were also determined. Cold exposure caused a significantly decreased rate of body weight gain and a highly significant transient hypertrophy of the adrenals. There was no significant change in the metabolic activity and chemical constituents of the testes. These data indicate that cold stress for 30 days has no significant effect on testis size, composition or metabolic activity in mature rats in which the hypothalamo\p=m-\adenohypophysial\p=m-\gonadal axis was stimulated by constant light.

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