Abstract
The combination of diuretics, angiotensin-converting enzyme (ACE) inhibitors, and, occasionally, digoxin has been recommended as the basis of treatment of chronic heart failure. Results of large clinical trials have shown that, although treatment with ACE inhibitors lessens admissions and improves survival,1 the addition of a β-blocker further reduces mortality.2,3 β-Blockers inhibit the long-term deleterious effects of the adrenergic nervous system on the heart and, thereby, improve the biologic functioning of the myocyte and ventricular chamber.
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Schedule a callMore From: Journal of the American Society of Echocardiography
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