Abstract
There are many reports in the literature about the critical role of the immune system in protecting the body against foreign agents. However, the role of immune status in the association of mycobacteriosis and fasciolosis has not been studied. The work aimed to investigate the effect of butaselmevit and closaverm A on the immune status of cows with experimental fasciolosis sensitized by atypical mycobacteria. For the trial, 15 cows of 4–5 years of age, black and spotted breed, were selected, from which 3 groups were formed, five animals in each. Cows of the first research group for experimental fasciolosis were injected intramuscularly with closaverm A at a dose of 0.5 ml of the drug per 10 kg of body weight. The animals of the second experimental group, for experimental fasciolosis, were intramuscularly injected with closaverm A at a dose of 0.5 ml of the drug per 10 kg of body weight and butaselmevit at a dose of 10 ml of the drug per animal. The obtained results indicate that the drugs “Klosaverm A” and “Butaselmevit” when administered intramuscularly to cows with experimental fasciolosis, sensitized by atypical mycobacteria, contribute to the activation of cellular and nonspecific links of immunity. It should be noted that a number of our research also established the stimulating effect of drugs on the humoral link of immunity, in particular, an increase in the bactericidal and lysozyme activity of blood serum of cows associated with mycobacteriosis and fasciolosis. Using “Klosaverm A” and “Butaselmevit” drugs in experimental groups of animals helped reduce the level of CIC to physiological values starting from the 21st day of the experiment. It should be noted that according to the indicators of the immune system in cows with experimental fasciolosis, sensitized by atypical mycobacteria, the combined use of closer A and butaselmevit shows a better therapeutic effect than the use of only closaverm A alone.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: Scientific Messenger of LNU of Veterinary Medicine and Biotechnologies
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.