Abstract
The brain lactate and ammonia levels increased and ATP, creatme phosphate and hexose phosphate levels decreased in a susceptible strain of rats when they were subjected to a prolonged auditory stimulus. The maximum changes in these compounds occurred during the catatonic phase of the seizure. There was a significant negative correlation between the rise in brain ammonia and fall in ATP. The possible sources of the endogenous brain ammonia formed during the seizure are discussed. A significant fall in adrenal ascorbic acid only occurred during the catatonic phase of the seizure.
Published Version
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