Abstract
The effect of age on chemical element mass fractions in intact prostate of 50 apparently healthy 0–30 year old males was investigated by neutron activation analysis with high resolution spectrometry of short-lived radionuclides. Mean values (M±SΕΜ) for mass fraction (mgkg−1, dry mass basis) of chemical elements before the time of puberty and in the period of puberty and post-puberty were: Br 46.0±6.7, Ca 1151±140, Cl 14572±700, K 10147±700, Mg 771±131, Mn 2.13±0.25, Na 9880±659 and Br 29.0±4.6, Ca 2049±364, Cl 11518±1121, K 13029±542, Mg 1186±134, Mn 1.74±0.16, Na 9887±716, respectively. A tendency of age-related increase in Ca, K, and Mg mass fraction and of age-related decrease in Br mass fraction was observed in period of life from 0 to 30 years. This new data indicates that of the elements studied, only the Ca, K, and Mg mass fraction in prostate tissue is an androgen-dependent parameter.
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