Abstract
1. 1. The uptake of glucose by extracts made from skeletal muscles of rats 50 to 60 minutes after subcutaneous injection of adrenaline (1 mg/kg) was investigated. 2. 2. When conditions were such that ATP resynthesis became important (experiments lasting half an hour or more in the absence of fluoride) the glucose utilization was markedly diminished. 3. 3. Under conditions where the original concentration of ATP was well maintained (short duration-experiments with addition of fluoride to inhibit ATP-ase) no diminution was observed. 4. 4. These facts seem to indicate that hexokinase is not affected but that there is a decreased rate of ATP resynthesis in the extracts obtained from animals treated with adrenaline.
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