Abstract
Central arterial stiffness is associated with incident hypertension and negative cardiovascular outcomes. Obese individuals have higher central blood pressure (BP) and central arterial stiffness than their normal‐weight counterparts, but it is unclear whether obesity also affects hemodynamics and central arterial stiffness after maximal exercise. We evaluated central hemodynamics and arterial stiffness during recovery from acute maximal aerobic exercise in obese and normal‐weight individuals. Forty‐six normal‐weight and twenty‐one obese individuals underwent measurements of central BP and central arterial stiffness at rest and 15 and 30 min following acute maximal exercise. Central BP and normalized augmentation index (AIx@75) were derived from radial artery applanation tonometry, and central arterial stiffness was obtained via carotid‐femoral pulse wave velocity (cPWV) and corrected for central mean arterial pressure (cPWV/cMAP). Central arterial stiffness increased in obese individuals but decreased in normal‐weight individuals following acute maximal exercise, after adjusting for fitness. Obese individuals also exhibited an overall higher central BP (P < 0.05), with no exercise effect. The increase in heart rate was greater in obese versus normal‐weight individuals following exercise (P < 0.05), but there was no group differences or exercise effect for AIx@75. In conclusion, obese (but not normal‐weight) individuals increased central arterial stiffness following acute maximal exercise. An assessment of arterial stiffness response to acute exercise may serve a useful detection tool for subclinical vascular dysfunction.
Highlights
Obese individuals have a higher prevalence of hypertension compared with their normal-weight counterparts (Fenske et al 2013; Vaneckova et al 2014)
Central arterial stiffness has been shown to be a key determinant of elevated central blood pressure (BP), another cardiovascular risk factor (Payne et al 2010)
Obese individuals have higher central BP and stiffer central arteries than normal-weight individuals (Kolade et al 2012). This is of clinical importance because increases in central BP, as well as in central arterial stiffness, have shown to be independent predictors of adverse a 2017 The Authors
Summary
Obese individuals have a higher prevalence of hypertension compared with their normal-weight counterparts (Fenske et al 2013; Vaneckova et al 2014). Obese individuals have higher central BP and stiffer central arteries than normal-weight individuals (Kolade et al 2012). This is of clinical importance because increases in central BP, as well as in central arterial stiffness, have shown to be independent predictors of adverse a 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.
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