Abstract
Summary. Young adult male rats were given 0·12 mg CdCl2/100 g b.wt by intraperitoneal injection and the resulting testicular degeneration was studied over a period of 3 months. The testicular degeneration due to a single injection of CdCl2 has been shown to have a profound effect on the weights of the testes, testicular total lipid and phospholipid and on the proportions of testicular phospholipid fatty acids. Increases in the percentage of 18:0, 18:2ω6, 20:3ω6, 20:4ω6 and 22:4ω6 and decreases in the percentage of 16:0, 22:5ω6 and 22:6ω3 were observed. The association of 22:5ω6 with spermatogenesis has been confirmed and it is suggested that nearly all the 22:5ω6 in the intact mature testis is located in the germinal epithelium, spermatids and spermatozoa.
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