THE EFFECT OF 2450 MHz MICROWAVE IRRADIATION ON THE LEVEL OF SEROTONIN IN RAT BRAIN FOLLOWING CHRONIC WHOLE BODY EXPOSURE

Abstract

Publisher Summary This chapter discusses a study to examine the effect of 245Q MHz microwave irradiation on the level of serotonin in rat brain following chronic whole body exposure. The study was conducted to examine the effects of chronic microwave radiation on the level of neurohormone serotonin in rat brain. As a source of microwave radiation, Power Signal Source AIL Type 125 was used. First group of six Albino 30 days old rats of one delivery litter size placed in perforated plastic cage were exposed individually every 24 hours through 49 days to 245Q MHz microwave radiation in waveguide system to a forward power of 0,5W and under field intensity of 8.26 mW/cm2. The rectal temperature of irradiated, rats was measured before, and immediately after exposure. Second group of six rats was shamirradiated and served as a control. Only in some exposure, the rise of rectal temperature was observed to be in range of 0.1 to 0.2°C. Irradiated as well as control animals were sacrificed by decapitation, the brain was quickly removed in liquid nitrogen and pulverized. The level of serotonin was estimated in brain homogenate samples according to spectrophotometric method of Fuller. Compared to the controls, irradiated animals showed significant decrease of serotonin level for 38%.