Abstract
The porous biphasic calcium phosphate ceramics composed of hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP) had been implanted the muscles of dogs and rabbits, respectively. We have investigated the early dissolution and deposition of calcium phosphate on the biphasic ceramics in varied animal species. The micrographs of biphasic ceramics after implanted were different between in dogs and rabbits. The X-ray diffraction patterns of biphasic ceramics showed the greater degradation in dogs than in rabbits the early stage in vivo. These results argue that the equilibrium between dissolution and deposition of biphasic calcium phosphate are different among various amimal species, which may result in the differential tissue response to the biphasic ceramics.
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