Abstract
The coronary vascular system is characterised by a small blood-volume, high resistance arterial system, in which flow is primarily diastolic, a capillary-venule exchange system and a large blood volume, low resistance venous system with predominately systolic flow. In order to understand the venous component we measured intramyocardial pressure (IMP), peripheral (PVP) and central (CVP) coronary venous pressure, as well as phasic coronary sinus outflow. Based on the experimental data, a model is proposed to describe the hemodynamics of the coronary venous system. This model consists of an intramyocardial vascular storage region into which the arterial blood flows during diastole. During systole, the pressure in the storage vessels increases, pushing the peripheral and epicardial venous system. Blocking the inflow tends to empty the ‘storage’ and the peripheral regions, reducing venous pressures. Occlusion of the outflow increases the blood volume in these regions, elevating venous pressures. The observations of peak (IMP-PVP) vs peak venous flow during vagal, right and left stellate stimulation conform satisfactorily with the model.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
