Abstract

Obviously, nemertean tissues normally have antibiotic properties, intensifyed by injury and in contact with bacteria. The highest antibiotic activity was found in mature nemertines, especially in females during the reproductive season. During winter, the antibiotic activity of tissue of the females in the damage focus is significantly reduced compared with the antibiotic activity of tissues during the reproductive period. In males, seasonal fluctuations of the antibiotic activity are negligible.Therefore, the antibiotic activity of the tissue regularly increases in the area of the wound track not only due to bacterial infection or the introduction of a foreign body, ensuring tissue sterility and preventing, thus, the development of necrosis, but also due to the physiological state of animals, particularly those related to reproductive cycles.

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