The discussion of risk factors of severe head injury with multiple organ dysfunction syndrome

Abstract

Objective To investigate the discussion of risk factors of severe head injury with multiple organ dysfunction syndrome. Methods The clinical data of 149 cases with severe traumatic brain injury patients were retrospectively analyzed, and the risk factors in patients with severe traumatic brain injury were collected, which may affect MODS, such as gender, age, GCS score,associated injuries, chronic underlying diseases, infections and other details, statistically analyzed were combined with incidence of MODS. Results (1)Univariate analysis results could be seen, age, chronic underlying diseases, admission GCS score, extensive brain parenchymal damage, merge large organ damage, brain herniation, concurrent infection, massive blood transfusion were risk factors of MODS severe traumatic brain injury(χ2=12.962,11.725,11.021,13.894,11.486,12.031, 12.967,13.078,P=0.023,0.025,0.027,0.017,0.023,0.018,0.021,0.019).(2)MODS rate and the number of risk factors were positive correlation(r=0.528,P=0.021).(3)With the increase of the number of mortality in patients with MODS organ dysfunction occurred significantly increased,MODS patients in this group,the two organs mortality was 17.4%,the three organs were 46.7%,four or more mortality was 87.5%(χ2=11.735,13.933,12.748,P=0.028,0.019,0.025). Conclusion Age, chronic underlying diseases, GCS low, extensive parenchymal injury, combined injury, the occurrence of hernia, complicated by infection, massive blood transfusion were independent risk factors for brain injury,which should be payed attention. Key words: Craniocerebral trauma; Multiple organ failure; Risk factors