Abstract

Objective To investigate the diagnostic values of procalcitonin (PCT),white blood cell (WBC) count,70% marginal values of neutral granular cell (NEU%) and C reactive protein (CRP) to old patients with sepsis.Methods An analysis was conducted including both 116 sepsis patients with positive blood culture and 50 patients with negative blood culture from January to December in 2013.The serum PCT,WBC,NEU% and CRP were tested.Results The levels of serum PCT,WBC,CRP and 70% marginal values NEU% in the positive blood culture group were significantly higher than those in the negative group (P < 0.05).Combination of PCT,WBC and NEU%,the sensitivity,specificity,positive predictive value,and negative predictive value were 82.4%,40%,52.6% and 74% respectively.PCT,WBC and NEU% might be considered respectively as single predictor through univariate and multivariate analysis in old patients with sepsis.Conclusion Serum PCT,WBC and NEU% may be used as markers in early diagnosis of sepsis.The combined determination of serum PCT,WBC and NEU% helps to exclude the diagnosis of sepsis. Key words: Blood culture; Sepsis; Procalcitonin; White blood cell count; Percentage of neutrophils

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