The Development of Site-directed Mutagenesis by Michael Smith

Nicole Kresge,Robert D Simoni,Robert L Hill

doi:10.1016/s0021-9258(19)33938-9

Abstract

The Development of Site-directed Mutagenesis by Michael Smith

Highlights

Michael Smith (1932–2000) was born in Blackpool, England, a working class town populated largely by coal miners and factory workers
During his last year of graduate school, Smith wrote to various American professors seeking a postdoctoral fellowship. He had no luck in obtaining his desired fellowship on the west coast of the United States, but he did hear of a young scientist in Vancouver, Canada, named Gobind Khorana, who might have a fellowship to work on the synthesis of biologically important organophosphates
Smith wrote to the future Nobel Laureate and was awarded a fellowship after an interview in London with the British Columbia Research Council

Summary

Introduction

Michael Smith (1932–2000) was born in Blackpool, England, a working class town populated largely by coal miners and factory workers. Smith wrote to the future Nobel Laureate and was awarded a fellowship after an interview in London with the British Columbia Research Council. In 1960, the Khorana group, along with Smith, moved to the Institute for Enzyme Research at the University of Wisconsin.

Results

Conclusion