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https://doi.org/10.1016/j.bmcl.2005.02.066
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Cite Publication Date: Mar 30, 2005 | |
 Citations: 54 |
4-Aryl-3-pyridyl and 4-aryl-3-pyrimidinyl based tumor necrosis factor-alpha (TNF-α) inhibitors, which contain a novel isoxazolone five-membered heterocyclic core are described. Many showed sub-micromolar activity against lipopolysaccharide-induced TNF-α production.
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