Abstract
In the computational biology, DNA strand displacement technique is used to construct the logic gate model and molecular circuits. But with the increase of number of the reaction strands, the basic logic gates cannot meet the accuracy in the reaction process. This paper improved the logical unit OR gate, AND gate to solve this problem on the basic of the seesaw model and the mechanism of DNA strand displacement reaction. Since the basic circuit of the decoder is an array of AND gates, the improvement module is applied to the decoder. The molecular circuit of decoder is constructed to realize the dynamic link between the input signal and the output signal. It is concluded that the sensitivity and accuracy of the improved decoder in the molecular circuit is improved by the Visual DSD software. The improvement module laid the foundation for the development of molecular circuits.
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