Abstract
Mass spectrometry (LC-MS or LC-MS/MS) appears in all phases of drug discovery and drug development areas. Starting with the screening and identification of a therapeutic agent and further measuring its in vivo and in vitro properties include: absorption, distribution, metabolism, excretion and toxicity (ADMET) and also pharmacokinetic (PK) and pharmacodynamic (PD) quantitative parameters of drug candidate. Mass spectrometry also serves as a necessary tool also to confirm purity and stability of analyzed new chemical entities (NCEs)/new molecular entities (NMEs) as well as for the analysis of degradation products from the synthesis and following on every stages of drug discovery.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call