Abstract
Obesity is mostly recognized as a chronic inflammatory condition in which the balance of normal state is destroyed and it is a risk of cardiovascular disease and many other chronic metabolic disease.Heme oxygenase-1(HO-1), a major cytoprotective enzyme, exerts significant antioxidant and anti-inflammatory effects.It also can improve the function of fat cells and enhanced insulin sensitivity in obese individuals.The researches of HO-1 for the anti-inflammatory effects and its intervention have great significance in improving the inflammatory state and its related diseases in obesity.This paper elaborates the change of HO-1 and its effect for macrophage infiltration in obesity. Key words: Obesity; Heme oxygenase-1; Inflammation; Macrophage infiltration
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