Abstract
Intensive attention has been drawn to macrophages in obesity after the discovery of macrophage infiltration in adipose tissue. This review updates of adipose tissue macrophages in the immune-pathophysiology of obesity, including new progression on the adipose tissue macrophages phenotype and the potential of beige fat induction by M2 macrophage, which inspires a novel therapy for obesity and insulin resistance. (Chin J Endocrinol Metab, 2017, 33: 236-241) Key words: Macrophage; Chronic inflammation; Obesity; Insulin resistance
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