Abstract
The compound 3β-acetoxy-5, 6β-dichloromethylene-5β-androstan-17-one crystallizes in the orthorhombic space group, P 2 1 2 1 2 1 , with four molecules per unit cell, having the following dimensions: a=7.936(2) A ̊ , b=11.593(2) A ̊ , and c=22.955(4) A ̊ . X-ray analysis of single crystal data (1764 observed reflections), collected on a Syntex P 1 auto-diffractometer, led to complete structural assignment. Solution by direct methods and refinement by least-squares calculations resulted in a final R of 0.037. The conformation of ring A represents one of the few examples of a distorted boat and ring B approximates a distorted chair, both conformations attributable to the strain of the cyclopropyl ring. The spatial relationship between the endo chlorine atom, and the angular methyl group, C(19) is 3.095(5) Å. Ring C is a normal chair and ring D adopts a 13β-envelope conformation. The steroid molecules pack perpendicular to the c axis with screw axes intersecting the A-B ring junction.
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