Abstract
Background: Diabetes mellitus and complications related to this disease have become a great problem affecting one in eleven adults. Pathophysiologically, this disease occurs due to impaired insulin secretion, resulting from systemic dysfunction in metabolic homeostasis involving inflammatory processes. One marker that can be used to measure such chronic inflammation is the neutrophil-lymphocyte ratio. Therefore, this study aims to evaluate the association between the neutrophil-to-lymphocyte ratio (NLR) with random blood glucose in patients with type 2 diabetes mellitus in Prof. Dr. I G. N. G. Ngoerah Hospital Methods: Our study is a cross-sectional study with secondary data from medical records and involved 155 type 2 diabetes mellitus patients who received inpatient or outpatient care at Prof. Dr. I G. N. G. Ngoerah Hospital in the period of 2021-2022. Results: Our analysis found a significant correlation between the neutrophil-lymphocyte ratio with random blood sugar levels (r = 0.228; p = 0.004). Additionally, the analysis also found a significant difference in random blood sugar level between the normal with the high neutrophil-lymphocyte ratio groups (p = 0.023; median difference = 39.5 mg/dL). Conclusion: It can be inferred that there is a weak and significant correlation between NLR with random blood glucose level in type 2 diabetes mellitus patients.
Published Version
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